UK will help track Covid variants in Brazil, Pakistan and Africa

Public Health England will help track Covid variants in Brazil, Pakistan and Africa to stamp out mutant strains before they go global

  • UK will provide genomic sequencing support in Ethiopia, Kenya and Nigeria 
  • PHE support comes through the New Variant Assessment Platform (NVAP)
  • Dominic Raab hails UK as ‘science superpower’ in global fight against Covid

British health officials will help track Covid variants abroad with the hopes of shutting down troubling new strains before they become widespread.

Public Health England said it will train up research labs in countries that lack the means to analyse positive tests for signs of mutated viruses

The first countries to benefit from the project, known as the New Variant Assessment Platform, will be Brazil, Kenya, Nigeria, and Pakistan. 

Plans are also in development for the UK to collaborate with both the African Centre for Disease Control in Ethiopia, and Singapore.  

The nations will receive equipment to increase sequencing as well as technical advice and training from British experts.

Variants that can slip past vaccines are now the single biggest threat to the UK’s Covid fight, now that nearly nine in 10 adults have been jabbed at least once. 

Ministers praised the UK’s role as a ‘science superpower’ and said the country has a duty to lend expertise in the global fight against Covid as new variants emerge. 

Public Health England today said the UK will provide Covid genomic sequencing support to other countries, including Brazil, Ethiopia, Kenya, Nigeria and Pakistan. Pictured: A lab assistant uses a pipette to prepare Coronavirus RNA for sequencing at the Wellcome Sanger Institute that is operated by Genome Research in Cambridge

Name: Lambda or C.37

Where was it first spotted? 

The strain was first sequenced in Peru in August 2020. 

How many cases have there been in the UK?

Britain has sequenced seven cases of the variant.

Only one has been spotted in the last four weeks, with the strain making up less than 0.1 per cent of infections during the period. 

Where else has it been spotted?

The variant has been spotted in 30 other countries, including the US, Australia and Germany.

What mutations does it have?

It has two concerning mutations on its spike protein — known as L452Q and F490S.

The mutations are feared play a role in making it more infectious and able to dodge some immunity. 

Is it more infectious?

Scientists in Peru have claimed the mutation is more infectious because of its rapid spread in the country.

But there is no significant proof the virus is actually any more contagious than existing strains, including Delta. 

Is it more deadly? 

Experts insist there is no evidence to suggest it is deadlier, despite some doctors linking its spread to Peru having the world’s worst Covid mortality rate.

It comes after scientists warned today Britain could be left battling against a vaccine-resistant Covid variant if cases are allowed to spiral to 100,000 a day.

Sir Paul Nurse, director of the Francis Crick Institute, claimed letting the coronavirus rip may lead to another mutant strain arising in the UK, which could pose a threat to any hopes of a life without lockdown. 

But not all scientists monitoring the pandemic are convinced that the summer surge in cases will inevitably turn the UK into a variant factory. 

Seeking to play down the fears, the boss of Britain’s largest Covid surveillance centre pointed out variants are normally either vaccine resistant or more transmissible.

SARS-CoV-2, the coronavirus behind Covid, is constantly evolving and the majority of mutations are ‘benign’, according to Dr Jeff Barrett, of the Sanger Institute. 

The South African ‘Beta’ variant, which can dodge vaccine-triggered immunity, has failed to gain a foothold in the UK. But the more transmissible Indian ‘Delta’ variant quickly became dominant and now accounts for nine in ten cases.

Announcing the variant tracking programme abroad today, Foreign Secretary Dominic Raab said the new partnership would help prevent any new variants from spreading globally in the same way.

He said: ‘The UK is a science superpower and it is right that we share our expertise in the global fight against Covid. 

‘I welcome this partnership with Brazil, Ethiopia, Kenya, Nigeria, Pakistan, Singapore and the Africa Centre for Disease Control and Prevention to identify, track and respond to new Covid variants and future health threats globally. 

‘No one is safe until we are all safe.’

The UK is also planning to work with the African Centre for Disease Control in Ethiopia and Singapore.

A technical advisor will be stationed in Ethiopia to provide guidance on sequencing across Africa.

Plans in Singapore are yet to be finalised but support is expected to be given to other countries in South East Asia.

Dr Jenny Harries, chief executive of the UK Health Security Agency, said: ‘Strong surveillance is vital to controlling the transmission of the virus and international co-operation is crucial in developing a system that works to protect all of us. 

‘The NVAP will provide valuable support to many international public health colleagues to strengthen their genomic sequencing capability, which in turn will make us all safer. 

‘New SARS-CoV-2 variants are a major threat and it is important to remember that in a global pandemic, no country is safe until all countries are safe.’

Health Secretary Sajid Javid added: ‘As we learn to live with Covid, we cannot underestimate the threat new variants could pose.

‘This ground-breaking genomics work — building on the phenomenal genomics expertise in the UK – will allow our global partners to identify variant cases of Covidand support us all to future-proof our way of life by preventing potential pandemics in the years ahead.

‘We are working arm-in-arm with nations to tackle this global pandemic, helping us all return to normality as quickly as possible by saving lives and protecting livelihoods.’

Sir Paul Nurse, director of the Francis Crick Institute, (left) warned today that high case numbers could spark a vaccine resistant variant. But Dr Jeff Barrett, who directs the largest Covid surveillance centre in the country, sought to play down the fears saying variants tend to be either more transmissible or vaccine resistant

More than 100 Britons could die each day from Covid when Britain finally emerges from lockdown later this month, according to the Government’s own assumptions. No10 said it expects up to 50,000 cases a day by July 19 Freedom Day and potentially 100,000 daily cases in August. Professor Neil Ferguson said about 0.1 per cent – or one in 1,000 – of people who catch Covid will die from the virus. The above graph shows how cases and deaths could rise based on these remarks. Deaths lag behind case spikes by about three weeks

Ministers warned yesterday cases in Britain could hit more than 100,000 cases a day next month, following ‘Freedom Day’ on July 19. 

The country is currently recording almost 30,000 a day, with the outbreak fuelled by the rapid spread of the Indian Delta variant.

Hospitalisations and deaths are now beginning to tick upwards but Health Secretary Sajid Javid yesterday insisted that the ‘wall of protection’ from vaccines would hold. 

Vaccines still work against the Indian mutant strain, drastically cutting the risk of infected people becoming severely ill. But Boris Johnson has already admitted the emergence of a vaccine-resistant variant could threaten plans in the future. 

Pfizer and Moderna vaccines work against Lambda variant 

Pfizer and Moderna’s Covid vaccines are both effective against the troublesome Lambda variant, scientists believe.

The mutant strain has now been spotted in 31 countries — and some doctors fear it is more transmissible than any existing versions.

But in a glimmer of hope, academics in New York say data suggests the variant is still susceptible to vaccines.

New York University Grossman School of Medicine researchers found antibodies triggered by MRNA jabs still neutralised the Lambda variant in laboratory studies.

It is not proof the jabs definitely work in thwarting the strain — but the scientists are confident.

Both Pfizer’s and Moderna’s vaccines are based on mRNA technology, which had never been used to make jabs until the Covid pandemic.

The mutant strain caught the attention of World Health Organization bosses after it was spotted in the UK, US and Germany.

Thought to have originated in Peru last summer, it quickly spiralled and now makes up 80 per cent of the South American country’s cases. 

Doctors monitoring its growth fear it spreads easier than other strains, including the Indian version that has caused havoc across the world. 

But coronavirus-tracking scientists are puzzled about the true transmissibility of the variant, given it was first spotted in Britain and February and has yet to take off.

They have yet to uncover any proof the variant is actually any more contagious than existing strains, including Delta or ‘Delta Plus’. Experts told MailOnline the variant is no reason to cancel or delay Freedom Day in the UK on July 19.

Others also insist there is no evidence to suggest it is deadlier, despite some doctors linking its spread to Peru having the world’s worst Covid mortality rate.

The new study, published in a preprint on BioRxiv, offers more hope the variant may not be any more dangerous than other strains already circulating.

Researchers tested samples of the Lambda variant against vaccine-elicited antibodies and ones triggered by powerful drugs — the experimental therapy given to President Donald Trump during his hospital stay with Covid last year.

It showed while the variant ‘showed a partial resistance’ to the antibodies created by the vaccines, the resistance ‘is not likely to cause a significant loss of protection against infection’. 


Dozens of variants have already been spotted across the world but none are thought to render the current crop of jabs useless.

And Oxford University academics who crafted the AstraZeneca jab say it is unlikely that any mutation will ever completely defeat vaccines.

But the spread of one that dodges immunity could still lead to a spike in hospital admissions and deaths, forcing ministers to divot from their plans. 

Sir Paul, a Nobel prize winning geneticist, told BBC Radio 4’s Today programme: ‘Letting [the] infection spread to large numbers of people… could give rise to another problem, which is encouraging new variants arising within the UK itself. 

‘We know that vaccinated people generally do not get serious disease but they are still getting infected. 

‘This is a situation which can select for variants, and that may give rise to variants that are resistant to the vaccine. 

He added: ‘If all controls are lifted and the virus is allowed to let rip, will that result in more resistant variants arising within the country itself which are more difficult to control?’ 

But Dr Barrett told the programme that although the virus is mutating all the time, the vast majority of these changes tend to be ‘benign’.

‘But then somewhat rarely the virus mutates in a way which makes it either more transmissible or less well neutralised by vaccines,’ he said.

‘We have seen that in the Alpha variant from last year and the Delta variant from this year, when they go from being sort of anonymous to taking over around the world very quickly.’

Asked whether a variant could emerge that is both more transmissible and more resistant to vaccines, he said: ‘One thing that seems to have happened so far is that many mutations are strongly associated either with increased transmissibility or evasion to antibodies, so basically the vaccines working less well.’

But he admitted high cases were ‘clearly one of the big risks’ in the Government’s unlocking strategy. 

Dr Barrett was also asked whether he was concerned about the Peruvian ‘Lamba’ variant, which emerged in August last year and has since exploded across South America.

But there have only been eight cases spotted in the UK so far, and there is no sign it is growing.

‘It is clearly at a high frequency in South America,’ he said. ‘But I don’t think it is inherently worrying.’

‘We should keep an eye on it but I don’t think there is any reason to panic just yet.’

He said the virus had key mutations that made it more transmissible, and that these were in a slightly different place compared to other faster spreading variants.

Professor Christina Pagel, a mathematician at University College London, echoed his view, telling MailOnline there was still little reason to be concerned.

‘I think Lambda is definitely a variant that we should be tracking, but I won’t be worried about it until it starts growing week on week and at the moment it’s too early to say,’ she said.

Only the more infectious Covid variants have managed to take hold in the UK so far, and displace other mutant strains.

The more infectious Kent variant spread across Britain within three months last year because of the N501Y mutation that made it more infectious.

But in early May it was replaced by the Indian variant which has the D614G and P681R mutations, which are thought to make it even more infectious.

Public Health England says it is at least 50 per cent more transmissible than the Kent strain. 

A ‘Delta plus’ variant has been detected which also carried the K417N mutation that makes it more resistant to vaccines, but it is yet to gain a foothold.  

The vaccine-resistant South African variant first arrived on Britain’s shores last year, but its cases have consistently remained below 100 every week.  

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